United States securities and exchange commission logo

                          March 18, 2021

       Chen Schor
       Chief Executive Officer
       Adicet Bio, Inc.
       500 Boylston Street, 13th Floor
       Boston, MA 02116

                                                        Re: Adicet Bio, Inc.
Statement on Form S-3
                                                            Filed March 12,
                                                            File No. 333-254193

       Dear Mr. Schor:

              This is to advise you that we have not reviewed and will not
review your registration

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact David
Gessert at 202-551-2326 with any questions.


                          Division of Corporation Finance

                          Office of Life Sciences